I was curious how much the lab costs to run per month, so I made the above plot. The outliers were usually from equipment purchases, which are labeled. The lab cost about $30k to run per month for the first few years (when we were personnel and space constrained), but has risen since. Over the last few months, it’s gone up to ~ $60k. This is part of the reason why government investment in basic not-for-immediate-profit biomedical research is so important, and why the purposeful partisan (ie. MAGA) cuts / disruption / dismantling of research funding is so devastating, since there’s no other entity (eg. private foundations, or companies) that is willing or able to step in when the rug is pulled out from us.